01910nas a2200169   4500008004100000245012000041210006900161260007100230300001400301490000700315520122800322100001201550700001301562700001501575700001301590856013701603       2004                        eng d00aMolecular population genetics of Cucumber mosaic virus in California: Evidence for founder effects and reassortment0 aMolecular population genetics of Cucumber mosaic virus in Califo  a1752 N ST NW, WASHINGTON, DC 20036-2904 USAbAMER SOC MICROBIOLOGY  a6666-66750 v783 aThe structure and genetic diversity of a California Cucumber mosaic virus (CMV) population was assessed by single-strand conformation polymorphism and nucleotide sequence analyses of genomic regions 2b, CP, MP, and the 3' nontranslated region of RNA3. The California CMV population exhibited low genetic diversity and was composed of one to three predominant haplotypes and a large number of minor haplotypes for specific genomic regions. Extremely low diversity and close evolutionary relationships among isolates in a subpopulation suggested that founder effects might play a role in shaping the genetic structure. Phylogenetic analysis indicated a naturally occurring reassortant between subgroup IA and IB isolates and potential reassortants between subgroup IA isolates, suggesting that genetic exchange by reassortment contributed to the evolution of the California CMV population. Analysis of various population genetics parameters and distribution of synonymous and nonsynonymous mutations revealed that different coding regions and even different parts of coding regions were under different evolutionary constraints, including a short region of the 2b gene for which evidence suggests possible positive selection.1 aLin, HX1 aRubio, L1 aSmythe, AB1 aFalk, BW  uhttps://nematoda.myspecies.info/content/molecular-population-genetics-cucumber-mosaic-virus-california-evidence-founder-effects-and-